Gene Detection and Precision Medicine

     The successful completion of the Human Genome Project and the application of parallel sequencing technology have made considerable progress in molecular biology. With the progress of tumor molecular biology research, the detection of circulating blood free DNA and the study of its biological indicators will likely provide a series of convenient, fast, specific, non-invasive or minimally invasive and molecular biological detection methods for early diagnosis, prognosis determination and follow-up of clinical tumors. Relevant experts said that circulating free nucleic acid test, or "liquid biopsy", could replace invasive biopsy.
      

   At present, the diagnosis of infectious diseases mainly depends on pathogenic and immunological diagnostic technologies, but the existing technologies still have many shortcomings in specificity, sensitivity and other aspects. Molecular diagnosis technology has the advantages of fast speed, high specificity, high sensitivity, and quantitative dynamic tracking. Especially in the detection of drug-resistant mutations, it shows more and more obvious advantages in the diagnosis and differential diagnosis of infectious diseases. In addition, with the advantage of high throughput of gene detection, parallel detection of multiple pathogenic microorganisms of related syndromes can be realized, which is conducive to accurate diagnosis and treatment of diseases. For example, comprehensive detection of upper respiratory tract infection, comprehensive detection of digestive tract infection, comprehensive detection of fever and rash, comprehensive detection of reproductive tract infectious diseases that cause infertility and fetal dysplasia, etc.